Publikacje

Piecyk K, Pietrow P, Arnold T, Worch R, Korneeva N.L, Jankowska-Anyszka M. (2020) Effect of HIV‑1 TAT Peptide Fusion on 5′ mRNA Cap Analogs Cell Membrane Permeability and Translation Inhibition, Bioconjugate  Chemistry 31, 1156-1166

Piecyk K, Łukaszewicz M, Kamel K, Janowska M, Pietrow P, Kmiecik S, Jankowska-Anyszka M. (2020) Isoxazole-containing 5’ mRNA cap analogues as inhibitors of the translation initiation process, Bioorganic Chemistry, https://doi.org/10.1016/j.bioorg.2020.103583

Pietrow P, Ferenc-Mrozek A, Piecyk K, Bojarska E, Darzynkiewicz E, Jankowska-Anyszka (2019) Decapping Scavenger Enzyme Activity toward N2-Substituted 5′ End mRNA Cap Analogues, ACS Omega. 2019 Oct 9;4(17):17576-17580

Koćmik I, Piecyk K, Rudzinska M, Niedzwiecka A, Darzynkiewicz E, Grzela R, Jankowska-Anyszka M. (2018) Modified ARCA analogs providing enhanced translational properties of capped mRNAs, Cell Cycle 17(13), 1624-1636

Grzela R, Nasilowska K, Lukaszewicz M, Tyras M, Stepinski J, Jankowska-Anyszka M, Bojarska E, Darzynkiewicz E. (2018) Hydrolytic activity of human Nudt16 enzyme on dinucleotide cap analogs and short capped oligonucleotides, RNA. 24(5), 633-642

Piecyk, K., Krynska, P., Kaluzna, J., Jankowska-Anyszka, M. (2017): Synthesis of the first double-functionalized dinucleotide mRNA cap analogue for its specific labeling, Tetrahedron Letters 58 (31), 3037-3040

Worch, R., Piecyk, K., Kolasa, A. B., Jankowska-Anyszka, M. (2016): Translocation of 5′ mRNA cap analogue — peptide conjugates across the membranes of giant unilamellar vesicles, Biochimica et Biophysica Acta (BBA) – Biomembranes, 1858 (2), 311-317.

Piecyk, K., Darzynkiewicz, Z. M., Jankowska-Anyszka, M., Ferenec-Mrozek, A., Stepinski, J., Darzynkiewicz, E. Bojarska, E. (2015): Effect of different N7 substitution of dinucleotide cap analogs on the hydrolytic susceptibility towards scavenger decapping enzymes (DcpS), Biochem. Biophys. Res. Commun. 464, 89-93.

Piecyk, K., Niedzwiecka, A., Ferenc-Mrozek, A., Lukaszewicz, M., Darzynkiewicz, E., Jankowska-Anyszka, M. (2015): How to find the optimal partner—studies of snurportin 1 interactions with U snRNA 5’ TMG-cap analogues containing modified 2-amino group of 7-methylguanosine, Bioorganic & Medicinal Chemistry 23 (15), 4660-4668.

Piecyk, K., Jankowska-Anyszka, M. (2014): Chemical conjugation of an mRNA cap analogue with a cell-penetrating peptide as a potential membrane permeable translation inhibitor, Tetrahedron Letters 55, 606–609.

Piecyk, K., Lukaszewicz, M., Darzynkiewicz.E., Jankowska-Anyszka, M. (2014): Triazole-containing monophosphate mRNA cap analogs as effective translation inhibitors, RNA  20, 1539-1547.

Piecyk, K., Davis, R.E., Jankowska-Anyszka, M. (2012): 5´-Terminal chemical capping of spliced leader RNAs, Tetrahedron Letters 53: 4843-4847.

Piecyk K., Davis R.E., Jankowska-Anyszka M.* (2012): Synthesis of 13C- and 14C-labeled dinucleotide mRNA cap anlogues for structural and biochemical studies, Bioorganic and Medicinal Chemistry Letters 22: 4391-4395.

Piecyk K., Davis R.E., Jankowska-Anyszka M.* (2012): Synthesis of N2-modified 7-methylguanosine 5’-monophosphates as nematode translation inhibitors, Bioorganic and Medicinal Chemistry 20: 4781-4789.

Jankowska-Anyszka, M., Karczmarczyk, M., Bulska, E. (2012): Elektroforeza żelowa: podstawy i zastosowanie do badania połączeń platyny z białkami,  monografia „Analityka platynowców”, Wydawnictwo Malamut, ISBN 978-83-934442-1-2

Liu, W.Z., Jankowska-Anyszka, M., Piecyk, K., Dickson, L., Wallace, A., Niedzwiecka, A., Stepinsk,i J., Stolarski, R., Darzynkiewicz, E., Kieft, J., Zhao, R., Jones, D.N.M., Davis, R.E.  (2011): Structural basis for nematode eIF4E binding an m(2,2,7)G-Cap and its implications for translation initiation, Nucleic Acids Research 39 (20): 8820-8832.

Jankowska-Anyszka, M., Piecyk, K., Samonina-Kosicka, J. (2011):  Synthesis of a new class of ribose functionalized dinucleotide cap analogues for biophysical studies on interaction of cap-binding proteins with the 5 ‚ end of mRNA, Organic and Biomolecular Chemistry 15: 5564-5572.

Jankowska-Anyszka, M., Piecyk, K. (2011): Dinucleotide cap analogue affinity resins for purification of proteins that specifically recognize the 5 ‚ end of mRNA, Bioorganic and Medicinal Chemistry Letters 21 (20): 6131-6134.

Benarroch, D., Jankowska-Anyszka, M., Stepinski, J., Darzynkiewicz, E., Shuman, S. (2010): Cap analog substrates reveal three clades of cap guanine-N2 methyltransferases with distinct methyl acceptor specificities, RNA 16 (1): 211-220.

Wypijewska, A., Bojarska, E., Stepinski, J., Jankowska-Anyszka, M., Jemielity, J., Davis, R.E., Darzynkiewicz, E. (2010):  Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies, FEBS Journal 277 (14), 3003-3013.

Wallace, A., Filbin, M.E., Veo B., McFarland, C., Stepinski, J., Jankowska-Anyszka, M., Darzynkiewicz, E., Davis, R.E. (2010): The Nematode Eukaryotic Translation Initiation Factor 4E/G Complex Works with a trans-Spliced Leader Stem-Loop To Enable Efficient Translation of Trimethylguanosine-Capped RNAs, Molecular and Cellular Biology 30 (8), 1958-1970.

Worch, R., Jankowska-Anyszka, M., Niedzwiecka, A., Stepinski, J., Mazza, C., Darzynkiewicz, E., Cusack, S., Stolarski, R. (2009): Diverse role of  three tyrosines in binding of the RNA 5’ cap to the human nuclear Cap Binding Complex, Journal of Molecular Biology 385, 618-627.

Liu, W.Z., Zhao, R., McFarland, C., Kieft, J., Niedzwiecka, A., Jankowska-Anyszka, M., Stepinski, J., Darzynkiewicz, E., Jones, D.N.M., Davis, R.E. (2009): Structural Insights into Parasite eIF4E Binding Specificity for m(7)G and m(2,2,7)G mRNA Caps, Journal of Biological Chemistry 284 (45): 31336-31349.

Wypijewska, A., Bojarska, E., Stępiński, J., Jankowska-Anyszka, M., Davis, R.E., Darzynkiewicz, E. (2008): Novel ribose modified dinucleotide cap analogue: Synthesis and hydrolytic susceptibility to scavanger decapping enzyme, Chemistry of Nucleic Acid Components, (Collection Symposium Series) 10, 457-460.

Wierzchowski, J., Pietrzak, M., Stepinski, J., Jemielity, J., Kalek, M., Bojarska, E., Jankowska-Anyszka, M., Davis, R.E., Darzynkiewicz, E. (2007): Kinetics of C elegans DcpS cap hydrolysis studied by fluorescence spectroscopy, Nucleosides Nucleotides & Nucleic Acids 26 (10-12): 1211-1215.

Darzynkiewicz, Z.M., Bojarska, E., Stepinski, J., Jemielity, J., Jankowska-Anyszka, M., Davis, R.E., Darzynkiewicz, E. (2007): Affinity of dinucleotide cap analogues for human decapping scavenger (hDcpS), Nucleosides Nucleotides & Nucleic Acids  26 (10-12): 1349-1352.

Cheng, G.F., Cohen, L., Mikhli, C., Jankowska-Anyszka, M., Stepinski, J., Darzynkiewicz, E., Davis, R.E. (2007): In vivo translation and stability of trans-spliced mRNAs in nematode embryos, Molecular &. Biochemical Parasiology  153 (2): 95-106.

Stachelska, A., Wieczorek, Z., Stepinski, J., Jankowska-Anyszka, M., Lonnberg, H.L., Darzynkiewicz, E. (2006): Kinetics of the imidazolium ring-opening of mRNA 5′-cap analogs in aqueous alkali, Collection of Czechoslovak Chemical Communications 71 (4): 567-578.

Jankowska-Anyszka, M., Nogalski, M., Darzynkiewicz, E. (2005): New affinity resin for purification of cap-binding proteins, Nucleosides Nucleotides & Nucleic Acids 24, (5-7): 503-506.

Worch, R., Stepinski, J., Niedzwiecka, A., Jankowska-Anyszka, M., Mazza, C., Cusack, S., Stolarski, R., Darzynkiewicz, E. (2005): Novel way of capping mRNA trimer and studies of its interaction with human nuclear cap-binding complex, Nucleosides Nucleotides & Nucleic Acids 24 (5-7): 1131-1134.

Worch, R., Niedzwiecka, A., Stepinski, J., Mazza, C., Jankowska-Anyszka, M., Darzynkiewicz, E., Cusack,   S., Stolarski, R. (2005): Specificity of recognition of mRNA 5 ‚ cap by human nuclear cap-binding complex, RNA 11, 1355-1363.

Worch, R., Niedzwiecka, A., Stepinski, J., Jankowska-Anyszka, M., Mazza, C., Darzynkiewicz, E., Cusack, S., Stolarski, R. (2005): Significance of the first transcribed nucleoside of capped RNA for ligand-induced folding of the cap-binding complex, Journal of Physics: Condensed Matter 17, S1495-S1503.

Yoffe, Y., Zuberek, J., Lewdorowicz, M., Zeira, Z., Keasar, C., Orr-Dahan, I., Jankowska-Anyszka, M., Stepinski, J., Darzynkiewicz, E., Shapira, M. (2004): Cap-binding activity of an eIF4E homolog from Leishmania, RNA 10, 1764-1775.

Lall, S., Friedman, C.C., Jankowska-Anyszka, M., Stepinski, J., Darzynkiewicz, E., Davis, R.E. (2004): Contribution of trans-splicing, 5 ‚-leader length, cap-poly(A) synergism, and initiation factors to nematode translation in an Ascaris suum embryo cell-free system, The Journal of Biological Chemistry 279, 45573-45585.

Cohen, L.S., Mikhli, C., Friedman, C., Jankowska-Anyszka, M., Stepinski, J., Darzynkiewicz, E., Davis, R.E. (2004): Nematode M(7)GpppG and m(3)(2,2,7)GpppG decapping: activities in Ascaris embryos and characterization of C. elegans scavenger DcpS, RNA 10, 1609-1624

Grudzien, E., Stepinski, J., Jankowska-Anyszka, M., Stolarski, R., Darzynkiewicz, E., Rhoads, R.E. (2004): Novel cap analogs for in vitro synthesis of mRNAs with high translational efficiency, RNA 10, 1479-1487

Niedźwiecka, A., Marcotrigiano, J., Stępiński, J., Jankowska-Anyszka, M., Wysłouch-Cieszyńska, A., Dadlez, M., Gingras, A-C., Mak, P., Darżynkiewicz, E., Sonenberg, N., Burley, S., Stolarski, R. (2002): Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5’ cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins, Journal of Molecular Biology 319, 615-635.

Stachelska, A., Wieczorek, Z., Ruszczyńska, K., Stolarski, R., Pietrzak, M., Lamphear, B.J., Rhoads, R.E., Darżynkiewicz, E., Jankowska-Anyszka M. (2002): Interaction of three Caenorhabditis elegans isoforms of translation factor eIF4E with mono- and trimethylated mRNA 5’ cap analogues, Acta Biochimica Polonica 49, 671-682.

Miyoshi, H., Dwyer, D.S., Keiper, B.D., Jankowska-Anyszka, M., Darżynkiewicz, E., Rhoads, R.E., (2002): Discrimination between mono- and trimethylated cap structures by two isoforms of Caenorhabditis elegans eIF4E, The EMBO Journal 21, 4680-4690.

Stępiński, J., Jankowska-Anyszka, M., Darżynkiewicz, E. (2002): Synteza ważnych biologicznie dinukleotydów z wiązaniem 5′,5′-oligofosforanowym, w „Na pograniczu chemii i biologii”, Tom V, str. 105-138, Wydawnictwo Naukowe UAM, Poznań

Stepinsk,i J., Jemielity, J., Lewdorowicz, M., Jankowska-Anyszka, M., Darzynkiewicz, E. (2002): Catalytic efficiency of divalent metal salts in dinucleoside 5’,5’-triphosphate bond formationChemistry of Nucleic Acid Components, (Collection Symposium Series) 5, 154-158.

Keiper, B. D., Lamphear, B.J., Deshpande, A.M., Jankowska-Anyszka, M., Aamodt, E.J., Blumenthal, T.E., Rhoads, R.E. (2000): Functional characterization of five eIF4E isoforms in Caenorhabditis elegans, The Journal of Biological Chemistry 275(14), 10590-10596.

Jankowska-Anyszka, M., Darzynkiewicz, E. (2000): Struktura i funkcja końca 5′ (kapu) mRNA i U snRNA, w „Na pograniczu chemii i biologii”, Tom IV, str. 143-179, Wydawnictwo Naukowe UAM, Poznań

 Bojarska, E., Kraciuk, R., Wierzchowski, J., Wieczorek, Z., Stępiński, J., Jankowska, M., Starzyńska, E., Guranowski, A., Darżynkiewicz, E. (1999): Hydrolysis of some mRNA 5’-cap analogs catalyzed by the human Fhit protein and lupin ApppA hydrolases, Nucleosides & Nucleotides 18, 1125-1126.

Niedźwiecka-Kornaś, A., Przedmojski, R., Balaspiri, L., Stępiński, J., Jankowska, M., Lonnberg, H., Darżynkiewicz, E., Stolarsk,i R. (1999): Studies on association of mRNA cap-analogues with a synthetic dodecapeptide DGIEPMWEDEKN, Nucleosides & Nucleotides 18, 1105-1106.

Cai, A., Jankowska-Anyszka, M., Centers, A., Chlebicka, L., Stępiński, J., Stolarski, R., Darżynkiewicz, E., Rhoads, R. E. (1999): Quantitative assessment of mRNA cap analogues as inhibitirs of in vitro translation, Biochemistry 38, 8538-8547.

Wieczorek, Z., Niedźwiecka-Kornaś, A., Chlebicka, L., Jankowsk,a M., Kiraga, K., Stępiński, J., Dadle,z M., Drabent, R., Darżynkiewic,z E., Stolarski, R. (1999): Fluorescence studies on association of human translation initiation factor eIF4E with mRNA cap-analogues, Zeitschrift für Naturforschung 54c, 278-284.

Lampio, A., Ahola, T., Darżynkiewicz, E., Stępiński, J., Jankowska-Anyszka, M., Kääriäinen, L. (1999): Guanosine nucleotide analogs as inhibitors of alphavirus mRNA capping enzyme, Antiviral Research 42, 35-46.

Niedzwiecka-Kornas, A., Chlebicka, L., Stepinski, J., Jankowska-Anyszka, M., Wieczorek, Z., Darzynkiewicz E., Rhoads R.E. (1999): Spectroscopic studies on association of mRNA cap-analogues with human translation factor eIF4E. From modelling of interactions to inhibitory properties, Chemistry of Nucleic Acid Components, (Collection Symposium Series) 2, 214-218.

Jankowska-Anyszka, M., Lamphear, B.J., Aamondt, E.J., Harrington, T., Darzynkiewicz, E.,  Stolarski, R., Rhoads, R.E. (1998): Multiple Isoforms of Eukaryotic Protein Synthesis Initiation Factor 4E in Caenorhabditis elegans can distinguish between mono- and trimethylated mRNA cap structures, Journal of Biological Chemistry 273, 10538-10542.

Wieczorek, Z., Zdanowski, K., Chlebicka, L. Stępiński, J., Jankowska, M., Kierdaszuk, B., Temeriusz, A., Darżynkiewic,z E., Stolarski, R. (1997): Fluorescence and NMR studies of intramolecular stacking of mRNA cap-analogues, Biochimica et Biophysica Acta 1354, 145-152.

Maroney, P.A., Yu, Y.-T., Jankowska, M., Nielsen, T.W. (1996): Direct analysis of nematode cis– and trans– spliceosomes: A functional role for U5 snRNA in spliced leader addition trans-splicing and the identification of novel Sm snRNPs, RNA 2, 735-745.

Bojarska, E., Stępiński, J., Guranowski, A., Starzyńska, E., Chlebicka, L., Jankowska, M., Darżynkiewicz, E. (1996): Hydrolitic susceptibilities of modified 5’-mRNA cap analogues to the yellow lupin Ap3A and Ap4A hydrolases, Collection of Czechoslovak Chemical Communications 61, 192- 196.

Stolarski, R., Zdanowski, K., Chlebicka, L., Wieczorek, Z., Sitek, A., Stępiński, J., Jankowska, M., Mattinen, J., Temeriusz, A., Darżynkiewicz, E. (1996): Inter- and intramolecular stacking of mRNA cap-analogues – relevance to initiation translation, Collection of Czechoslovak Chemical Communications 61, 217-221.

Jankowska, M., Stępiński, J., Stolarski, R., Wieczorek, Z., Temeriusz, A., Haber, D., Darżynkiewicz, E. (1996): 1H NMR and fluorescence studies of new mRNA 5′-cap analogues, Collection of Czechoslovak Chemical Communications 61, 197- 202.

Stolarsk,i R., Sitek, A., Stępiński, J., Jankowska, M., Oksman, P., Temeriusz, A., Darżynkiewicz, E., Lonnberg, H., Shugar, D. (1996): 1H-NMR studies on association of mRNA cap-analogues with tryptophan-containing peptides, Biochimica et Biophysica Acta  1293, 97-105.

Wieczorek, Z., Stępiński, J., Jankowska, M., Lonnber,g, H. (1995): Fluorescence and absorption spectroscopic properties of RNA 5’-cap analogues derived from 7-methyl-, N2,7-dimethyl- and N2,N2,7-trimethylguanosines, Journal of Photochemistry and Photobiology B: Biology 28,57-63.

Stępiński, J., Bretner, M., Jankowska, M., Felczak, K., Stolarski, R., Wieczorek, Z., Cai, A.-L., Rhoads, R.E., Temeriusz, A., Haber, D., Darżynkiewicz, E. (1995): Synthesis and properties of P1,P2 -, P1,P3 -, P1,P4 – dinucleoside di-, tri- and tetraphosphate mRNA 5’-cap analogues, Nucleosides & Nucleotides 14, 717-721.

Izaurralde, E., Lewis, J., McGuigan, C., Jankowska, M., Darżynkiewicz, E., Mattaj, I.W. (1994): A nuclear Cap Binding Protein Complex involved in pre-mRNA splicing, Cell 78, 657-668.

Jankowska, M., Temerius,z A., Stolarski, R., Darżynkiewicz, E. (1993): Synthesis of m22,7GTP- and m32,2,7GTP-Sepharose 4B: new affinity resin for isolation of Cap Binding Proteins, Collection of Czechoslovak Chemical Communications 58, ss132-137.

Jankowska, M., Stępiński, J., Stolarski, R., Temeriusz, A., Darżynkiewicz, E. (1993): Synthesis and properties of new NH2 and N7 substituted GMP and GTP 5’-mRNA cap analogues, Collection of Czechoslovak Chemical Communications 58, ss138-141.